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AIM2-Like Receptors Positively and Negatively Regulate the Interferon Response Induced by Cytosolic DNA

Cytosolic DNAs derived from retrotransposons serve as pathogen-associated molecular patterns for pattern recognition receptors (PRRs) that stimulate the induction of interferons (IFNs) and other cytokines, leading to autoimmune disease. Cyclic GMP-AMP synthase is one PRR that senses retrotransposon...

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Detalles Bibliográficos
Autores principales:	Nakaya, Yuki, Lilue, Jingtao, Stavrou, Spyridon, Moran, Eileen A., Ross, Susan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573678/ https://www.ncbi.nlm.nih.gov/pubmed/28679751 http://dx.doi.org/10.1128/mBio.00944-17

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