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Chaperone co-inducer BGP-15 inhibits histone deacetylases and enhances the heat shock response through increased chromatin accessibility

Defects in cellular protein homeostasis are associated with many severe and prevalent pathological conditions such as neurodegenerative diseases, muscle dystrophies, and metabolic disorders. One way to counteract these defects is to improve the protein homeostasis capacity through induction of the h...

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Detalles Bibliográficos
Autores principales: Budzyński, Marek A., Crul, Tim, Himanen, Samu V., Toth, Noemi, Otvos, Ferenc, Sistonen, Lea, Vigh, Laszlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573690/
https://www.ncbi.nlm.nih.gov/pubmed/28474205
http://dx.doi.org/10.1007/s12192-017-0798-5