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Chaperone co-inducer BGP-15 inhibits histone deacetylases and enhances the heat shock response through increased chromatin accessibility
Defects in cellular protein homeostasis are associated with many severe and prevalent pathological conditions such as neurodegenerative diseases, muscle dystrophies, and metabolic disorders. One way to counteract these defects is to improve the protein homeostasis capacity through induction of the h...
Autores principales: | Budzyński, Marek A., Crul, Tim, Himanen, Samu V., Toth, Noemi, Otvos, Ferenc, Sistonen, Lea, Vigh, Laszlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573690/ https://www.ncbi.nlm.nih.gov/pubmed/28474205 http://dx.doi.org/10.1007/s12192-017-0798-5 |
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