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Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics

There is growing interest in using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) derivatives for tissue regeneration. However, an increased understanding of human immune responses to stem cell-derived allografts is necessary for maintaining long-term graft persistence. To model...

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Detalles Bibliográficos
Autores principales: Kooreman, Nigel G., de Almeida, Patricia E., Stack, Jonathan P., Nelakanti, Raman V., Diecke, Sebastian, Shao, Ning-Yi, Swijnenburg, Rutger-Jan, Sanchez-Freire, Veronica, Matsa, Elena, Liu, Chun, Connolly, Andrew J., Hamming, Jaap F., Quax, Paul H.A., Brehm, Michael A., Greiner, Dale L., Shultz, Leonard D., Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573767/
https://www.ncbi.nlm.nih.gov/pubmed/28834758
http://dx.doi.org/10.1016/j.celrep.2017.08.003