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Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections
A diverse and well-balanced repertoire of T cells is thought to be crucial for the efficacious defence against infection with new or re-emerging pathogens throughout life. In the last third of the mammalian lifespan, the maintenance of a balanced T-cell repertoire becomes highly challenging because...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573867/ https://www.ncbi.nlm.nih.gov/pubmed/18469829 http://dx.doi.org/10.1038/nri2318 |