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Understanding the mTOR signaling pathway via mathematical modeling

The mechanistic target of rapamycin (mTOR) is a central regulatory pathway that integrates a variety of environmental cues to control cellular growth and homeostasis by intricate molecular feedbacks. In spite of extensive knowledge about its components, the molecular understanding of how these funct...

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Detalles Bibliográficos
Autores principales: Sulaimanov, Nurgazy, Klose, Martin, Busch, Hauke, Boerries, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573916/
https://www.ncbi.nlm.nih.gov/pubmed/28186392
http://dx.doi.org/10.1002/wsbm.1379