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Myosin II activity is required for structural plasticity at the axon initial segment

In neurons, axons possess a molecularly defined and highly organised proximal region – the axon initial segment (AIS) – that is a key regulator of both electrical excitability and cellular polarity. Despite existing as a large, dense structure with specialised cytoskeletal architecture, the AIS is s...

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Detalles Bibliográficos
Autores principales: Evans, Mark D., Tufo, Candida, Dumitrescu, Adna S., Grubb, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573965/
https://www.ncbi.nlm.nih.gov/pubmed/28452088
http://dx.doi.org/10.1111/ejn.13597