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Separating Thermodynamics from Kinetics—A New Understanding of the Transketolase Reaction
Transketolase catalyzes asymmetric C−C bond formation of two highly polar compounds. Over the last 30 years, the reaction has unanimously been described in literature as irreversible because of the concomitant release of CO(2) if using lithium hydroxypyruvate (LiHPA) as a substrate. Following the re...
Autores principales: | Marsden, Stefan R., Gjonaj, Lorina, Eustace, Stephen J., Hanefeld, Ulf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573996/ https://www.ncbi.nlm.nih.gov/pubmed/28919932 http://dx.doi.org/10.1002/cctc.201601649 |
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