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Concerted functions of Streptococcus gordonii surface proteins PadA and Hsa mediate activation of human platelets and interactions with extracellular matrix

A range of Streptococcus bacteria are able to interact with blood platelets to form a thrombus (clot). Streptococcus gordonii is ubiquitous within the human oral cavity and amongst the common pathogens isolated from subjects with infective endocarditis. Two cell surface proteins, Hsa and Platelet ad...

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Detalles Bibliográficos
Autores principales: Haworth, Jennifer A., Jenkinson, Howard F., Petersen, Helen J., Back, Catherine R., Brittan, Jane L., Kerrigan, Steve W., Nobbs, Angela H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574023/
https://www.ncbi.nlm.nih.gov/pubmed/27616700
http://dx.doi.org/10.1111/cmi.12667