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Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity

Immunotherapy using broadly neutralizing antibodies (bNAbs) endowed with Fc-mediated effector functions has been shown to be critical for protecting or controlling viral replication in animal models. In human, the RV144 Thai trial was the first trial to demonstrate a significant protection against H...

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Detalles Bibliográficos
Autores principales: Bernard, Nicole F., Kiani, Zahra, Tremblay-McLean, Alexandra, Kant, Sanket A., Leeks, Christopher E., Dupuy, Franck P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574056/
https://www.ncbi.nlm.nih.gov/pubmed/28883824
http://dx.doi.org/10.3389/fimmu.2017.01033