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Differential analysis between somatic mutation and germline variation profiles reveals cancer-related genes
A major aim of cancer genomics is to pinpoint which somatically mutated genes are involved in tumor initiation and progression. We introduce a new framework for uncovering cancer genes, differential mutation analysis, which compares the mutational profiles of genes across cancer genomes with their n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574113/ https://www.ncbi.nlm.nih.gov/pubmed/28841835 http://dx.doi.org/10.1186/s13073-017-0465-6 |