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Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1

BACKGROUND: To overcome the hostile hypoxic microenvironment of solid tumors, tumor cells secrete a large number of non-coding RNA-containing exosomes that facilitate tumor development and metastasis. However, the precise mechanisms of tumor cell-derived exosomes during hypoxia are unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Xue, Mei, Chen, Wei, Xiang, An, Wang, Ruiqi, Chen, He, Pan, Jingjing, Pang, Huan, An, Hongli, Wang, Xiang, Hou, Huilian, Li, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574139/
https://www.ncbi.nlm.nih.gov/pubmed/28841829
http://dx.doi.org/10.1186/s12943-017-0714-8