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The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas

Mutations in the telomerase reverse transcriptase gene promoter (TERTp) are common in glioblastomas (GBMs) and oligodendrogliomas (ODGs), and therefore, have a key role in tumorigenesis and may be of prognostic value. However, the extent of their prognostic importance in various gliomas is controver...

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Detalles Bibliográficos
Autores principales: Lee, Yujin, Koh, Jaemoon, Kim, Seong-Ik, Won, Jae Kyung, Park, Chul-Kee, Choi, Seung Hong, Park, Sung-Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574236/
https://www.ncbi.nlm.nih.gov/pubmed/28851427
http://dx.doi.org/10.1186/s40478-017-0465-1