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Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets

Islet amyloid and beta cell death in type 2 diabetes are heterogeneous events, where some islets are affected early in the disease process, whereas others remain visibly unaffected. This study investigated the possibility that inter-islet functional and vascular differences may explain the propensit...

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Detalles Bibliográficos
Autores principales: Ullsten, Sara, Bohman, Sara, Oskarsson, Marie E, Nilsson, K Peter R, Westermark, Gunilla T, Carlsson, Per-Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574281/
https://www.ncbi.nlm.nih.gov/pubmed/28790139
http://dx.doi.org/10.1530/EC-17-0148