Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis

11β-Hydroxysteroid dehydrogenase-1 (11β-HSD1) predominantly converts inert glucocorticoids into active forms, thereby contributing to intracellular glucocorticoid levels. 11β-HSD1 is dynamically regulated during inflammation, including in macrophages where it regulates phagocytic capacity. The resol...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenguang, Coutinho, Agnes E, Man, Tak Yung, Kipari, Tiina M J, Hadoke, Patrick W F, Salter, Donald M, Seckl, Jonathan R, Chapman, Karen E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574305/
https://www.ncbi.nlm.nih.gov/pubmed/28676523
http://dx.doi.org/10.1530/JOE-17-0223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574305/
https://www.ncbi.nlm.nih.gov/pubmed/28676523
http://dx.doi.org/10.1530/JOE-17-0223

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