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Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis

11β-Hydroxysteroid dehydrogenase-1 (11β-HSD1) predominantly converts inert glucocorticoids into active forms, thereby contributing to intracellular glucocorticoid levels. 11β-HSD1 is dynamically regulated during inflammation, including in macrophages where it regulates phagocytic capacity. The resol...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhenguang, Coutinho, Agnes E, Man, Tak Yung, Kipari, Tiina M J, Hadoke, Patrick W F, Salter, Donald M, Seckl, Jonathan R, Chapman, Karen E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574305/ https://www.ncbi.nlm.nih.gov/pubmed/28676523 http://dx.doi.org/10.1530/JOE-17-0223

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