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Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis

OBJECTIVES: To seek evidence of the danger molecule, high-mobility group protein B1 (HMGB1) expression in human tendinopathy and thereafter, to explore mechanisms where HMGB1 may regulate inflammatory mediators and matrix regulation in human tendinopathy. METHODS: Torn supraspinatus tendon (establis...

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Detalles Bibliográficos
Autores principales: Akbar, Moeed, Gilchrist, Derek S, Kitson, Susan M, Nelis, Briana, Crowe, Lindsay A N, Garcia-Melchor, Emma, Reilly, James H, Kerr, Shauna C, Murrell, George A C, McInnes, Iain B, Millar, Neal L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574425/
https://www.ncbi.nlm.nih.gov/pubmed/28879051
http://dx.doi.org/10.1136/rmdopen-2017-000456