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Improving ethanol yield in acetate-reducing Saccharomyces cerevisiae by cofactor engineering of 6-phosphogluconate dehydrogenase and deletion of ALD6

BACKGROUND: Acetic acid, an inhibitor of sugar fermentation by yeast, is invariably present in lignocellulosic hydrolysates which are used or considered as feedstocks for yeast-based bioethanol production. Saccharomyces cerevisiae strains have been constructed, in which anaerobic reduction of acetic...

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Detalles Bibliográficos
Autores principales: Papapetridis, Ioannis, van Dijk, Marlous, Dobbe, Arthur PA, Metz, Benjamin, Pronk, Jack T., van Maris, Antonius J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574463/
https://www.ncbi.nlm.nih.gov/pubmed/27118055
http://dx.doi.org/10.1186/s12934-016-0465-z