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Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infraorbital blood–nerve barrier following chronic constriction injury?

BACKGROUND: Blood–nerve barrier disruption is pivotal in the development of neuroinflammation, peripheral sensitization, and neuropathic pain after peripheral nerve injury. Activation of toll-like receptor 4 and inactivation of Sonic Hedgehog signaling pathways within the endoneurial endothelial cel...

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Detalles Bibliográficos
Autores principales: Moreau, Nathan, Mauborgne, Annie, Couraud, Pierre-Olivier, Romero, Ignacio A, Weksler, Babette B, Villanueva, Luis, Pohl, Michel, Boucher, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574482/
https://www.ncbi.nlm.nih.gov/pubmed/28814148
http://dx.doi.org/10.1177/1744806917727625