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Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infraorbital blood–nerve barrier following chronic constriction injury?
BACKGROUND: Blood–nerve barrier disruption is pivotal in the development of neuroinflammation, peripheral sensitization, and neuropathic pain after peripheral nerve injury. Activation of toll-like receptor 4 and inactivation of Sonic Hedgehog signaling pathways within the endoneurial endothelial cel...
Autores principales: | Moreau, Nathan, Mauborgne, Annie, Couraud, Pierre-Olivier, Romero, Ignacio A, Weksler, Babette B, Villanueva, Luis, Pohl, Michel, Boucher, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574482/ https://www.ncbi.nlm.nih.gov/pubmed/28814148 http://dx.doi.org/10.1177/1744806917727625 |
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