High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease

Polycystic kidney disease (PKD) is a prevalent disorder characterized by renal cysts that lead to kidney failure. Various signaling pathways have been targeted to stop disease progression, but most interventions still focus on alleviating PKD-associated symptoms. The mechanistic complexity of the di...

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Detalles Bibliográficos
Autores principales: Booij, Tijmen H., Bange, Hester, Leonhard, Wouter N., Yan, Kuan, Fokkelman, Michiel, Kunnen, Steven J., Dauwerse, Johannes G., Qin, Yu, van de Water, Bob, van Westen, Gerard J. P., Peters, Dorien J. M., Price, Leo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574491/
https://www.ncbi.nlm.nih.gov/pubmed/28644734
http://dx.doi.org/10.1177/2472555217716056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574491/
https://www.ncbi.nlm.nih.gov/pubmed/28644734
http://dx.doi.org/10.1177/2472555217716056

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