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Comparative study of different methodologies to detect the JAK2 V617F mutation in chronic BCR-ABL1 negative myeloproliferative neoplasms

OBJECTIVES: A mutation in the JAK2 gene, V617F, has been identified in several BCR-ABL1 negative myeloproliferative neoplasms (MPN): polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Defining the presence or absence of this mutation is an essential part of clin...

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Detalles Bibliográficos
Autores principales: Didone, Alline, Nardinelli, Luciana, Marchiani, Mariana, Ruiz, Antonio Roberto Lancha, de Lima Costa, Ariel Lais, Lima, Ismael Severino, Santos, Nathalia Moreira, Sanabani, Sabri Saeed, Bendit, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574508/
https://www.ncbi.nlm.nih.gov/pubmed/28856190
http://dx.doi.org/10.1016/j.plabm.2015.12.004