Early-onset behavioral and neurochemical deficits in the genetic mouse model of phenylketonuria

Phenylketonuria (PKU) is one of the most common human inborn errors of metabolism, caused by phenylalanine hydroxylase deficiency, leading to high phenylalanine and low tyrosine levels in blood and brain causing profound cognitive disability, if untreated. Since 1960, population is screened for hype...

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Detalles Bibliográficos
Autores principales: Fiori, Elena, Oddi, Diego, Ventura, Rossella, Colamartino, Marco, Valzania, Alessandro, D’Amato, Francesca Romana, Bruinenberg, Vibeke, van der Zee, Eddy, Puglisi-Allegra, Stefano, Pascucci, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574541/
https://www.ncbi.nlm.nih.gov/pubmed/28850618
http://dx.doi.org/10.1371/journal.pone.0183430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574541/
https://www.ncbi.nlm.nih.gov/pubmed/28850618
http://dx.doi.org/10.1371/journal.pone.0183430

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