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Defects in skeletal muscle subsarcolemmal mitochondria in a non-obese model of type 2 diabetes mellitus

Skeletal muscle resistance to insulin is related to accumulation of lipid-derived products, but it is not clear whether this accumulation is caused by skeletal muscle mitochondrial dysfunction. Diabetes and obesity are reported to have a selective effect on the function of subsarcolemmal and interfi...

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Detalles Bibliográficos
Autores principales: Lai, Nicola, Kummitha, China, Hoppel, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574550/
https://www.ncbi.nlm.nih.gov/pubmed/28850625
http://dx.doi.org/10.1371/journal.pone.0183978