Dynactin has two antagonistic regulatory domains and exerts opposing effects on dynein motility

Dynactin is a dynein-regulating protein that increases the processivity of dynein movement on microtubules. Recent studies have shown that a tripartite complex of dynein–dynactin–Bicaudal D2 is essential for highly processive movement. To elucidate the regulation of dynein motility by dynactin, we f...

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Detalles Bibliográficos
Autores principales: Kobayashi, Takuya, Miyashita, Takuya, Murayama, Takashi, Toyoshima, Yoko Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574551/
https://www.ncbi.nlm.nih.gov/pubmed/28850609
http://dx.doi.org/10.1371/journal.pone.0183672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574551/
https://www.ncbi.nlm.nih.gov/pubmed/28850609
http://dx.doi.org/10.1371/journal.pone.0183672

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