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Apolipoprotein L1 risk variants associate with prevalent atherosclerotic disease in African American systemic lupus erythematosus patients

OBJECTIVE: Atherosclerosis is exaggerated in African American (AA) systemic lupus erythematosus (SLE) patients, with doubled cardiovascular disease (CVD) risk compared to White patients. The extent to which common Apolipoprotein L1 (APOL1) risk alleles (RA) contribute to this trend is unknown. This...

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Detalles Bibliográficos
Autores principales: Blazer, Ashira, Wang, Binhuan, Simpson, Danny, Kirchhoff, Tomas, Heffron, Sean, Clancy, Robert M., Heguy, Adriana, Ray, Karina, Snuderl, Matija, Buyon, Jill P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574561/
https://www.ncbi.nlm.nih.gov/pubmed/28850570
http://dx.doi.org/10.1371/journal.pone.0182483