RASSF1A hypermethylation is associated with ASXL1 mutation and indicates an adverse outcome in non-M3 acute myeloid leukemia

OBJECTIVE: The purpose of this study was to evaluate the frequency of RASSF1A hypermethylation in patients with acute myeloid leukemia (AML), in an attempt to modify the current molecular model for disease prognosis. MATERIALS AND METHODS: Aberrant RASSF1A promoter methylation levels were assessed i...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Gong, Ming, Gao, Li, Cai, Xiaoping, Zhang, Hui, Ma, Yigai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574588/
https://www.ncbi.nlm.nih.gov/pubmed/28860824
http://dx.doi.org/10.2147/OTT.S142528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574588/
https://www.ncbi.nlm.nih.gov/pubmed/28860824
http://dx.doi.org/10.2147/OTT.S142528

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