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Sensitization of gastric cancer cells to alkylating agents by glaucocalyxin B via cell cycle arrest and enhanced cell death

Severe side effects are major problems with chemotherapy of gastric cancer (GC). These side effects can be reduced by using sensitizing agents in combination with therapeutic drugs. In this study, the low/nontoxic dosage of glaucocalyxin B (GLB) was used with other DNA linker agents mitomycin C (MMC...

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Detalles Bibliográficos
Autores principales: Ur Rahman, Muhammad Saif, Zhang, Ling, Wu, Lingyan, Xie, Yuqiong, Li, Chunchun, Cao, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574593/
https://www.ncbi.nlm.nih.gov/pubmed/28860714
http://dx.doi.org/10.2147/DDDT.S145719