T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria

Th1 cells can be activated by TCR-independent stimuli, but the importance of this pathway in vivo and the precise mechanisms involved require further investigation. Here, we used a simple model of non-cognate Th1 cell stimulation in Salmonella-infected mice to examine these issues. CD4 Th1 cell expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pham, Oanh H., O’Donnell, Hope, Al-Shamkhani, Aymen, Kerrinnes, Tobias, Tsolis, Renée M., McSorley, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574617/
https://www.ncbi.nlm.nih.gov/pubmed/28817719
http://dx.doi.org/10.1371/journal.ppat.1006566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574617/
https://www.ncbi.nlm.nih.gov/pubmed/28817719
http://dx.doi.org/10.1371/journal.ppat.1006566

Ejemplares similares