Vaccination with poly(D,L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with a TNFα-mimicking peptide or monophosphoryl lipid A confers protection against experimental visceral leishmaniasis

Visceral leishmaniasis (VL) persists as a major public health problem, and since the existing chemotherapy is far from satisfactory, development of an effective vaccine emerges as the most appropriate strategy for confronting VL. The development of an effective vaccine relies on the selection of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Margaroni, Maritsa, Agallou, Maria, Athanasiou, Evita, Kammona, Olga, Kiparissides, Costas, Gaitanaki, Catherine, Karagouni, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574665/
https://www.ncbi.nlm.nih.gov/pubmed/28883727
http://dx.doi.org/10.2147/IJN.S141069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574665/
https://www.ncbi.nlm.nih.gov/pubmed/28883727
http://dx.doi.org/10.2147/IJN.S141069

Ejemplares similares