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Vaccination with poly(D,L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with a TNFα-mimicking peptide or monophosphoryl lipid A confers protection against experimental visceral leishmaniasis
Visceral leishmaniasis (VL) persists as a major public health problem, and since the existing chemotherapy is far from satisfactory, development of an effective vaccine emerges as the most appropriate strategy for confronting VL. The development of an effective vaccine relies on the selection of the...
Autores principales: | Margaroni, Maritsa, Agallou, Maria, Athanasiou, Evita, Kammona, Olga, Kiparissides, Costas, Gaitanaki, Catherine, Karagouni, Evdokia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574665/ https://www.ncbi.nlm.nih.gov/pubmed/28883727 http://dx.doi.org/10.2147/IJN.S141069 |
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