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Doxorubicin-loaded redox-responsive micelles based on dextran and indomethacin for resistant breast cancer

Multidrug resistance (MDR) against chemotherapeutic agents has become one of the major obstacles to successful cancer therapy and MDR-associated proteins (MRPs)-mediated drug efflux is the key factor for MDR. In this study, a redox-responsive polymer based on dextran (DEX) and indomethacin (IND), wh...

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Detalles Bibliográficos
Autores principales: Zhou, Yunfang, Wang, Shuanghu, Ying, Xuhua, Wang, Yifan, Geng, Peiwu, Deng, Aiping, Yu, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574666/
https://www.ncbi.nlm.nih.gov/pubmed/28883726
http://dx.doi.org/10.2147/IJN.S141229