Rotavirus NSP1 Requires Casein Kinase II-Mediated Phosphorylation for Hijacking of Cullin-RING Ligases

The rotavirus nonstructural protein NSP1 repurposes cullin-RING E3 ubiquitin ligases (CRLs) to antagonize innate immune responses. By functioning as substrate adaptors of hijacked CRLs, NSP1 causes ubiquitination and proteasomal degradation of host proteins that are essential for expression of inter...

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Detalles Bibliográficos
Autores principales: Davis, Kaitlin A., Morelli, Marco, Patton, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574712/
https://www.ncbi.nlm.nih.gov/pubmed/28851847
http://dx.doi.org/10.1128/mBio.01213-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574712/
https://www.ncbi.nlm.nih.gov/pubmed/28851847
http://dx.doi.org/10.1128/mBio.01213-17

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