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Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs

Genes encoding proteins that carry out essential informational tasks in the cell, in particular where multiple interaction partners are involved, are less likely to be transferable to a foreign organism. Here, we investigated the constraints on transfer of a gene encoding a highly conserved informat...

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Detalles Bibliográficos
Autores principales: Kacar, Betül, Garmendia, Eva, Tuncbag, Nurcan, Andersson, Dan I., Hughes, Diarmaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574714/
https://www.ncbi.nlm.nih.gov/pubmed/28851849
http://dx.doi.org/10.1128/mBio.01276-17