Activation of invariant natural killer T cells stimulated with microbial α-mannosyl glycolipids

Some synthetic and bacterial glycolipids presented by CD1d specifically activate invariant NKT (iNKT) cells bearing an invariant Vα14-Jα18 (mouse) or Vα24-Jα18 (human) TCR. The antigenic glycolipids identified to date consist of two hydrophobic chains and an α-glycoside in which the 2′-OH group is i...

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Detalles Bibliográficos
Autores principales: Shimamura, Michio, Yamamura, Masaki, Nabeshima, Tatsuya, Kitano, Naoki, van den Elzen, Peter, Yesilkaya, Hasan, Andrew, Peter, Illarionov, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574887/
https://www.ncbi.nlm.nih.gov/pubmed/28852174
http://dx.doi.org/10.1038/s41598-017-10309-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574887/
https://www.ncbi.nlm.nih.gov/pubmed/28852174
http://dx.doi.org/10.1038/s41598-017-10309-x

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