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Sphingosine 1-Phosphate Signaling as a Target in Hepatic Fibrosis Therapy

Liver fibrosis is an excess production of extracellular matrix proteins as a result of chronic liver disease which leads to cell death and organ dysfunction. The key cells involved in fibrogenesis are resident hepatic stellate cells (HSCs) which are termed myofibroblasts after activation, acquiring...

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Detalles Bibliográficos
Autores principales: González-Fernández, Bárbara, Sánchez, Diana I., González-Gallego, Javier, Tuñón, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574909/
https://www.ncbi.nlm.nih.gov/pubmed/28890699
http://dx.doi.org/10.3389/fphar.2017.00579