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Sphingosine 1-Phosphate Signaling as a Target in Hepatic Fibrosis Therapy
Liver fibrosis is an excess production of extracellular matrix proteins as a result of chronic liver disease which leads to cell death and organ dysfunction. The key cells involved in fibrogenesis are resident hepatic stellate cells (HSCs) which are termed myofibroblasts after activation, acquiring...
Autores principales: | González-Fernández, Bárbara, Sánchez, Diana I., González-Gallego, Javier, Tuñón, María J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574909/ https://www.ncbi.nlm.nih.gov/pubmed/28890699 http://dx.doi.org/10.3389/fphar.2017.00579 |
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