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Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo

Outer membrane vesicles (OMVs) are proteoliposomes blebbed from the surface of Gram-negative bacteria. Chronic periodontitis is associated with an increase in subgingival plaque of Gram-negative bacteria, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia. In this study, we inve...

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Detalles Bibliográficos
Autores principales: Cecil, Jessica D., O’Brien-Simpson, Neil M., Lenzo, Jason C., Holden, James A., Singleton, William, Perez-Gonzalez, Alexis, Mansell, Ashley, Reynolds, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574916/
https://www.ncbi.nlm.nih.gov/pubmed/28890719
http://dx.doi.org/10.3389/fimmu.2017.01017