A novel automatic quantification method for high-content screening analysis of DNA double strand-break response

High-content screening is commonly used in studies of the DNA damage response. The double-strand break (DSB) is one of the most harmful types of DNA damage lesions. The conventional method used to quantify DSBs is γH2AX foci counting, which requires manual adjustment and preset parameters and is usu...

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Detalles Bibliográficos
Autores principales: Feng, Jingwen, Lin, Jie, Zhang, Pengquan, Yang, Songnan, Sa, Yu, Feng, Yuanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574919/
https://www.ncbi.nlm.nih.gov/pubmed/28852024
http://dx.doi.org/10.1038/s41598-017-10063-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574919/
https://www.ncbi.nlm.nih.gov/pubmed/28852024
http://dx.doi.org/10.1038/s41598-017-10063-0

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