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An enhanced C. elegans based platform for toxicity assessment

There is a well-defined regulatory framework governing the approval of chemicals for use as pharmaceuticals or release into the environment. Toxicity assessment is thus a major hurdle in the compound discovery pipeline, currently involving large scale animal testing. The search for alternative testi...

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Detalles Bibliográficos
Autores principales: Xiong, Huajiang, Pears, Catherine, Woollard, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575006/
https://www.ncbi.nlm.nih.gov/pubmed/28852193
http://dx.doi.org/10.1038/s41598-017-10454-3