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Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration

Microtubule-stabilizing drugs have gained popularity for treating injured adult axons, the rationale being that increased stabilization of microtubules will prevent the axon from retracting and fortify it to grow through inhibitory molecules associated with nerve injury. We have posited that a bette...

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Detalles Bibliográficos
Autores principales: Austin, Timothy O., Matamoros, Andrew J., Friedman, Joel M., Friedman, Adam J., Nacharaju, Parimala, Yu, Wenqian, Sharp, David J., Baas, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575010/
https://www.ncbi.nlm.nih.gov/pubmed/28852085
http://dx.doi.org/10.1038/s41598-017-10250-z