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Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration
Microtubule-stabilizing drugs have gained popularity for treating injured adult axons, the rationale being that increased stabilization of microtubules will prevent the axon from retracting and fortify it to grow through inhibitory molecules associated with nerve injury. We have posited that a bette...
Autores principales: | Austin, Timothy O., Matamoros, Andrew J., Friedman, Joel M., Friedman, Adam J., Nacharaju, Parimala, Yu, Wenqian, Sharp, David J., Baas, Peter W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575010/ https://www.ncbi.nlm.nih.gov/pubmed/28852085 http://dx.doi.org/10.1038/s41598-017-10250-z |
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