Cargando…

Evolutionary conserved role of eukaryotic translation factor eIF5A in the regulation of actin-nucleating formins

Elongation factor eIF5A is required for the translation of consecutive prolines, and was shown in yeast to translate polyproline-containing Bni1, an actin-nucleating formin required for polarized growth during mating. Here we show that Drosophila eIF5A can functionally replace yeast eIF5A and is req...

Descripción completa

Detalles Bibliográficos
Autores principales: Muñoz-Soriano, Verónica, Domingo-Muelas, Ana, Li, Tianlu, Gamero, Esther, Bizy, Alexandra, Fariñas, Isabel, Alepuz, Paula, Paricio, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575014/
https://www.ncbi.nlm.nih.gov/pubmed/28852021
http://dx.doi.org/10.1038/s41598-017-10057-y