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Regulation of Orai1/STIM1 mediated I(CRAC) by intracellular pH

Ca(2+) release activated Ca(2+) (CRAC) channels composed of two cellular proteins, Ca(2+)-sensing stromal interaction molecule 1 (STIM1) and pore-forming Orai1, are the main mediators of the Ca(2+) entry pathway activated in response to depletion of intracellular Ca(2+) stores. Previously it has bee...

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Detalles Bibliográficos
Autores principales: Gavriliouk, D., Scrimgeour, N. R., Grigoryev, S., Ma, L., Zhou, F. H., Barritt, G. J., Rychkov, G. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575016/
https://www.ncbi.nlm.nih.gov/pubmed/28851859
http://dx.doi.org/10.1038/s41598-017-06371-0