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Skeletal Site-specific Changes in Bone Mass in a Genetic Mouse Model for Human 15q11-13 Duplication Seen in Autism

Children suffering from autism have been reported to have low bone mineral density and increased risk for fracture, yet the cellular origin of the bone phenotype remains unknown. Here we have utilized a mouse model of autism that duplicates 6.3 Mb region of chromosome 7 (Dp/+) corresponding to a reg...

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Detalles Bibliográficos
Autores principales: Lewis, Kirsty E., Sharan, Kunal, Takumi, Toru, Yadav, Vijay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575059/
https://www.ncbi.nlm.nih.gov/pubmed/28851986
http://dx.doi.org/10.1038/s41598-017-09921-8