Hypoxic Stress Decreases c-Myc Protein Stability in Cardiac Progenitor Cells Inducing Quiescence and Compromising Their Proliferative and Vasculogenic Potential

Cardiac progenitor cells (CPCs) have been shown to promote cardiac regeneration and improve heart function. However, evidence suggests that their regenerative capacity may be limited in conditions of severe hypoxia. Elucidating the mechanisms involved in CPC protection against hypoxic stress is esse...

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Detalles Bibliográficos
Autores principales: Bellio, Michael A., Pinto, Mariana T., Florea, Victoria, Barrios, Paola A., Taylor, Christy N., Brown, Ariel B., Lamondin, Courtney, Hare, Joshua M., Schulman, Ivonne H., Rodrigues, Claudia O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575078/
https://www.ncbi.nlm.nih.gov/pubmed/28851980
http://dx.doi.org/10.1038/s41598-017-09813-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575078/
https://www.ncbi.nlm.nih.gov/pubmed/28851980
http://dx.doi.org/10.1038/s41598-017-09813-x

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