Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders

Anti-idiotypic binders which specifically recognize the variable region of monoclonal antibodies have proven to be robust tools for pharmacokinetic studies of antibody therapeutics and for the development of cancer vaccines. In the present investigation, we focused on the identification of anti-idio...

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Detalles Bibliográficos
Autores principales: Könning, Doreen, Rhiel, Laura, Empting, Martin, Grzeschik, Julius, Sellmann, Carolin, Schröter, Christian, Zielonka, Stefan, Dickgießer, Stephan, Pirzer, Thomas, Yanakieva, Desislava, Becker, Stefan, Kolmar, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575089/
https://www.ncbi.nlm.nih.gov/pubmed/28852148
http://dx.doi.org/10.1038/s41598-017-10513-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575089/
https://www.ncbi.nlm.nih.gov/pubmed/28852148
http://dx.doi.org/10.1038/s41598-017-10513-9

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