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Creating the Functional Single-Ring GroEL-GroES Chaperonin Systems via Modulating GroEL-GroES Interaction

Chaperonin and cochaperonin, represented by E. coli GroEL and GroES, are essential molecular chaperones for protein folding. The double-ring assembly of GroEL is required to function with GroES, and a single-ring GroEL variant GroEL(SR) forms a stable complex with GroES, arresting the chaperoning re...

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Detalles Bibliográficos
Autores principales: Illingworth, Melissa, Ellis, Holly, Chen, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575113/
https://www.ncbi.nlm.nih.gov/pubmed/28852160
http://dx.doi.org/10.1038/s41598-017-10499-4