A unique tolerizing dendritic cell phenotype induced by the synthetic triterpenoid CDDO-DFPA (RTA-408) is protective against EAE

Tolerogenic dendritic cells (DCs) have emerged as relevant clinical targets for the treatment of multiple sclerosis and other autoimmune disorders. However, the pathways essential for conferring the tolerizing DC phenotype and optimal methods for their induction remain an intense area of research. T...

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Detalles Bibliográficos
Autores principales: Wei, Hsi-Ju, Pareek, Tej K., Liu, Qi, Letterio, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575165/
https://www.ncbi.nlm.nih.gov/pubmed/28851867
http://dx.doi.org/10.1038/s41598-017-06907-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575165/
https://www.ncbi.nlm.nih.gov/pubmed/28851867
http://dx.doi.org/10.1038/s41598-017-06907-4

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