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Reduced expression of Paternally Expressed Gene-3 enhances somatic cell reprogramming through mitochondrial activity perturbation

Imprinted genes control several cellular and metabolic processes in embryonic and adult tissues. In particular, paternally expressed gene-3 (Peg3) is active in the adult stem cell population and during muscle and neuronal lineage development. Here we have investigated the role of Peg3 in mouse embry...

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Detalles Bibliográficos
Autores principales: Theka, Ilda, Sottile, Francesco, Aulicino, Francesco, Garcia, Alvaro Castells, Cosma, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575273/
https://www.ncbi.nlm.nih.gov/pubmed/28852087
http://dx.doi.org/10.1038/s41598-017-10016-7